The Change Of Hematological Disease Constitute And The Analysis Of Related Factors For Patients Be Hospitalized In 28 Years

Objective: To analyze the constitution of hematologic diseases and the change of the numbers of inpatients in our hospital from 1980 to 2007 to find the rule and change in common hematologic diseases, and to provide scientific basis for the prevention and treatment of hematologic diseases in the city.Methods: 6286 patients with hematologic diseases from 1980 to 2007 were collected. All these cases were divided into 7 groups in sequence of time. Each group contained cases of continuous 4 years.Results:1.6286 cases with hematologic disease were diagnosed from 1980 to 2007, the number of patients increased gradually; total number of 340 patients hospitalized from 1980 to 1983, and the number increased to 2100 in years 2003-2007, increased 6.18 times. The leukemia was the most common disease, the total number was 1840 (29.2% of all), the following disease were:immune thrombocytopenia (ITP), iron deficiency anemia(IDA), aplastic anemia(AA), leukopenia and agranulocytosis, malignant lymphoma (ML), myelodysplastic syndrome(MDS), multiple myeloma(MM), megalo- blastic anemia(MA), autoimmune hemolytic anemia(AIHA). The numbers of leukemia, ITP and MDS apparently increased(P<0.01), the numbers aslo increased in AA,leukopenia and agranulocytosis, MM, MA, AIHA(P<0.05); although the numbers of IDA and ML cases increaseed, there was no significant difference(P> 0.05).2.The numbers of male and female patients both increased. Of the all 6286 patients, 2991 were male, and 3295 were female, male to female ratio was 1:1.1. Malignant diseases were more common in male than female.3.Patients of urban were more than the suburb. There was significant difference in benign hematologic diseases between urban and suburb(P <0.05); There was no significant difference in malignant hematologic diseases (P>0.05).4.Different diseases had the different age of onset. The age peak of incidence of leukemia was among 35-45 years old, and the ITP was among 14-25 years old, leukopenia and agranulocytosis were among 25-35 years old, ML was among 45-65 years old, MM was among 55-65 years old.Conclusions:1.The number of inpatients increased gradually from 1980 to 2007.2.Leukemia was the most common disease, and the total number was 1840 (29.2% of all). The first five diseases were leukemia, ITP, IDA, AA, and leukopenia and agranulocytosis.3.The ratio of male patients to female was 1:1.1. Malignant diseases were more common in male than female.4.The age peak of incidence of leukemia was among 35-45 years old, and the ITP was among 14-25 years old, leukopenia and agranulocytosis were among 25-35 years old, ML was among 45-65 years old, MM was among 55-65 years old.