30 Cases Of Clinical Observation Of Traditional Chinese Medicine Compound Capsule "Ai Keqing" United HAART For AIDS' Treatment

Objective:Currently the treatment principle of the AIDS mainly in order to repress the mankind the immunity blemish virus(HIV), the anti- opportunity sex appeal dye,the related tumor of the anti-,strengthen the machine body immunity function.The efficiently virus safe treatment(the HAART therapy) of the doctor has already can make the virus carried the quantity significant descend,the immunity reconstruction and the opportunity type infect the obvious decrease,but the HAART treatment can't completely exterminate the virus,and the medicine price is so expensive,so the sufferer has to take over a long period of time, and the output poisonous pair responds very greatly,and the easy creation depends on the poisonous stub of the medicine sexually transmitted disease,stopping the medicine future reunion rebound. These disadvantageous factors limit the further expansion of the HAART therapy.This topic passes the clinic observation to use "Ai Keqing" capsule consociation HAART treatment to 30 AIDS patients, and evaluates the "Ai Keqing " capsule curing the curative effect and the safety of the AIDS.Method:Choose the AIDS patients that are treated from March of 2007 to June of 2008 in the third people hospital of Shenzhen City, especially staying in the department of the hospital or out-patient service to carry on the HAART treatment 30 in order to cure the set. The examples win election from the case of the same period to take the condition alike,the CD 4+T Lymphoid cell,and the simplicity carries on the case of the HAART treatment 30 examples matched controls.Curing the set 30 use the Chinese herbal medicine compound prescribe "Ai Keqing" capsule(developed by the tropical disease researching institute of Guangzhou university of Chinese medicine ),at the time of entering the HAART treatment;matched control 30 the examples carry on the pure HAART treatment.Then we should record two sets of observation point of departures of cases respectively,and record the symptom body solicits integral,the Karnovsky solicits integral,the carrying quantity of HIV-RNA and the count of CD4+ T Lymphoid cell which are cured 6 and 12 months. Besides checking the liver and the kidney function and blood normal regulations.According to the contrast ion of the two sets or the curing set itself,we can appraise the effection and safety of the "Ai Keqing" capsule.Result:(a) The contrast ion of the curing set itself:â‘ treating the curing set 6 months comparing with the observation point of departure,its count of CD 4+ T Lymphoid cell obviously goes up(P<0.01),the symptom integral calculus descend(P<0.05),the Karnovsky solicits integral go up(P<0.05);â‘¡treating the curing set 12 months comparing with the observation point of departure, its count of CD 4+ T Lymphoid cell obviously goes up(P<0.01),the symptom integral calculus descend(P<0.05),the Karnovsky solicits integral go up(P<0.05);â‘¢comparing the 6 and 12 months curing, its count of CD 4+ T Lymphoid cell goes up not obviously(P>0.05), the symptom integral calculus descend(P>0.05),the Karnovsky solicits integral has no to obviously change(P>0.05),and before or after the treatment the function of liver and kidney and blood normal regulations is not changed obviously.(b) The contrast ion of the two sets:curing 6 months,the count of CD 4+ T Lymphoid cell of the two sets has obviously differentiation(P<0.05).curing 12 months the count of CD 4+ T Lymphoid cell of the two sets has difference but no significance of statistics(P>0.05).Conclusion:the Chinese herbal medicine compound prescribe "Ai Keqing" capsule consociating HAART treatment can improve clinical symptoms effectively of AIDS patients,improving the count of CD 4+ T Lymphoid cell,reducing the toxically side-effect when just using the medicine only,and enhancing the patients' complying. But the function of descending the carrying quantity of HIV-RNA is not obvious.It needs to be developed in the future research.