The Progression Of Mechanism, Prevention And Cure In Posterior Capsule Opacification

Posterior Capsule Opacification (PCO) is the most common complication of cataract surgery.At present, the only means of treating cataract is by surgical intervention, and this initially restores high visual quality.Unfortunately, PCO develops in a significant proportion of patients to such an extent that a secondary loss of vision occurs. A modern cataract operation generates a capsular bag, which comprises a proportion of the anterior and the entire posterior capsule.However, on the remaining anterior capsule, lens epithelial cells stubbornly reside despite enduring the rigours of surgical trauma.The mechanism of posterior capsule opacification is mainly related with migration ,proliferation and transdifferentiation of remain crystal epithelial cells. At present ,the main therapy aimming to it is laser incision of posterior capsule.This article reviewed the biological mechanisms driving PCO progression and discuss the influence of IOL design, surgical techniques and putative drug therapies in regulating the rate and severity of PCO.