| Objective:To observe the effect of Quyu Mixture to reduce early pregnancy medical abortion (hereinafter referred to as medical abortion) after the amount of vaginal bleeding and shorten time of the vaginal bleeding after medical abortion and decrease the incomplete abortion rate of uterine surgery.Methods:200 patients who were unconstraint to ask medical abortion reallocated randomly into 2 groups: treated group which contains 100 patients and antithetic group which contains 100 patients all patients taked orally 50mg Mifepristone at 9:00 a.m. and 25mg at p.m. in the first day and second day. They must be limosis for 2 hours before and after they were dosed, then came to the hospital to taked orally 600μg Misoprostol when they were limosis in the morning of the third day. They were asked to stay in hospital for 6 hours to be observed. After the sac was charging, patients of the treated group taked orally Quyu Mixture in this day, 100ml, B. I. D. , and they must continue to take the medicine for 7 days. The antithetic group taked orally Yimucao Granule for 7 days, 15g, B. I. D. .The two groups taked cefalexin capsules for 3 days, 0. 5g, daily four times. The cefalexin capsules allergy taked metronidazole for 3 days, 0.2g, B. I.D., in the Prevention of Infection. The two groups were observed effect of abortion, medical abortion bleeding after the number of days, amount of bleeding after medical abortion, the recovery period, the rate of uterine curettage, Chinese medicine syndromes.Results:The results showed that complete abortion rate of the treated group was 94 cases accounting for 94.00%, incomplete abortion rate was 6 cases accounting for 6.00%; and complete abortion of the antithetic group was 80 cases accounting for 80. 00%, incomplete abortion rate was 20 cases accounting for 20. 00% . As the improvement of the Chinese medicine syndromes , the treated group' s clinical cure was 40 cases, the marked effect was 27cases, the effective was 25cases , the ineffective was 8 cases, overall efficiency rate was 92.00% , and the antithetic group was respectively 27cases, 25cases, 26cases, 22cases, overall efficiency rate was 78. 00%. The statistics difference between them ws prominent, ( P< 0. 05) . The treated group' s bleeding duration of the vagina was (9. 90±4. 00) days, and the latter was (13. 92±5.0 ) days. The statistics difference between them was prominent, (P < 0. 05 ) . Two groups have significant difference in the constituent ratio of vaginal bleeding by analysis (P <0. 05 ) , This showed that the treated group reducing the vaginal bleeding after medical abortion more effective than the antithetic group. In treated group, those whose bleeding quantity was 17 cases more than catamenia account for 17. 00%; those whose bleeding quantity was 56 cases equal to catamenia account for 56. 00%; those whose bleeding quantity was 27 cases less than catamenia account for 27. 00%; and in the antithetic group was respectively 30cases, 43cases, 27cases, account for 30.00%, 43.00%, 27.00%. The statistics difference between them was prominent ( P < 0. 05 ). The treated group' s bleeding quantity was less than antithetic group. In the antithetic group, those whose uterine curettage was 20 cases account for 20. 00%; and in treated group was only 6 cases account for 6. 00%. The rate of the treated group was significantly lower than the antithetic group, two groups have significant difference (P<0. 05). From the medical abortion to menstruation coming, normally, the treated group was ( 30. 35±6. 12 ) days, and the antithetic group was ( 31. 45±5.50) days. The average day of menses resumption was ( 5. 85±2.10) days in the treated group; and this was (5. 89±3. 10) days in the antithetic group . Comparing between the two groups was not significant difference ( P>0. 05).Conclusion:Clinical observation above showed that Quyu Mixture could short the bleeding time, reduced the amount of bleeding, decrease the rate of uterine surgery. It had no bad effect for day of menses resumption, and no obvious side effects. It was a safe and effective prescription. Quyu Mixture could promote the further development of clinical medical abortion, but it only restricted to the observation of clinical effect lacking of basic experimental study. Next, we should be to study on the mechanism, and to develop content of active components, and to improve the form , in order to providing a more effective method that could deal with long time bleeding and bleeding amount after medical abortion, so that it could make medical abortion more safe and effective.
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