Clinical Study On Large Cavum Septum Pellucidum And Cavum Vergae In Fetus

Objective :To discuss the clinical significance of fetal large cavum septum pellucidum and cavum vergae by prenatal ultrasonography.Methods: Prenatal ultrasonography was performed on women at our hospital for prenatal diagnosis during January 2006 to April 2008.Totally 35 women with diagnosis and found that fetal large cavum septum pellucidum and cavum vergae were included in the study. The changes of fetal large cavum septum pellucidum and cavum vergae were observed regularly until delivery. The live infants were followed up regularly in one year.Results: Totally 35 women with fetal large cavum septum pellucidum and cavum vergae were included in the study. 25 cases of fetus were with large cavum vergae, 2 cases of fetus were with large cavum septum pellucidum, and 8 cases of fetus were with both large cavum septum pellucidum and cavum vergae. They were diagnosed between 26-37 gestational weeks, with a median of (31±3) weeks. In the pregnancy period, 14 cases of the large cavum septum pellucidum and cavum vergae were decreased, 10 cases were seen decreased to nomal degree. The expansion degree decreased cases compared to not decreased cases, have statistically significant(p<0.05). Fetus with nomal perinatal outcomes compared to abnormal, neither the expansion of their specific site types nor the expansion degree is statistically significant(p>0.05). 18 cases were with large cavum septum pellucidum and cavum vergae and not combined with other abnormalities, and 17 cases were combined with other abnormalities. Compared between the two, perinatal outcomes have significant difference (p <0.05). 11 cases of large cavum septum pellucidum and cavum vergae in fetus were combined with fetal encephalic fluid, compared to other anomalies, has statistically significant(p<0.05).Conclusion: Fetus with large cavum septum pellucidum and cavum vergae occur mainly in the second and third trimesters of pregnancy, when we found that the degree of the expansion degree of fetal large cavum septum pellucidum and cavum vergae decreased, it may be possible good signs of perinatal outcomes. Fetus with cavum vergae could be more commonly seen in the cases. The type and degree of large cavum septum pellucidum and cavum vergae do not affect perinatal outcomes. Fetal with large cavum septum pellucidum and cavum vergae could be combined with other intracranial and extracranial structures anomalies. The most cases are accompanied with fetal encephalic fluid . When the ultrasound examination diagnosis of large cavum septum pellucidum and cavum vergae, we should be close ultrasound follow-up of the size of cavum septum pellucidum and cavum vergae and other intracranial, extracranial structures anomalies. When ultrasound examination diagnosis are difficult, fetal MRI and karyotype analysis should be suggested.