The Study Of Correlation Between ABâ… , CRP And The Stenosis Severity Of Coronary Artery

Objective:To detect the correlation between that two parameters ABIandCRPand that stenosis severity in the patient with coronary artery diseaseMethods:The coronary artery graph was done on 85 selected patients include male 60 and female 25,the age ranges from42 to77,the mean is 59.58±10.06.Serum CRP of 85 patients were measured by Japanese Olympus AU640Automatic Analyzer with immunonephelometry and get the systolic artery press of ankle arteries(the maximal value of posterior tibial artery or dorsal pedal artery) and bilateral brachial arteries, then compute the data for ABI and analyzed with the minimal values, describe arterial stenosis severity with amounts of lesion vessels and Gensini score system.Divide the patients into two teams : three-branch team(test team) and nonthree-branch team(control team) according coronary arteriography.Results:1 There was significant difference in smoking, diabetes ABI,CRP,CSS between test team group and control team group(p=0.007,p=0.000)2 There is negative correlation between ABI and stenosis severity of lesion vessel(p=0.036)and positive correlation between CRP and stenosis severity of lesion vessel(p=0.036).3 The CRP area under ROC curve is(o.893±0.035), 95℅confidence interval is (0.082～0.963);ABI data is (0.706±0.056)and(0.569～0.816).4 Multiple linear gression equation illustrate that the CHD can be estimated by The diabete(sr=-3.647,wald=4.517P=0.033), smoking history (r=-0.252 , wald=3.947, p=0.047) and ABI (r=51.012,wald=9.158, p=0.002)Conclusions:1 there is negative correlation between CHD and stenosis severity of coronary artery ,the level of the ABI ,the more severity of the stenosis vessel; the positive correlation between CRP and stenosis severity of coronary artery.2 Coronary artery disease can be estimated by ABI and CRP ,but in some way, ABI is better than CRP in estimating coronary artery disease.