A Systematic Review Of Heat-clearing Therapy For Rheumatoid Arthritis In The Active Stage

Objective: Summarize the complexion of heat-clearing therapy for Rheumatoid Arthritis in the Active Stage in summary; Compare the clinical curative effect of different heat-clearing therapy, search the best heat-clearing Formula of chinese medicine for Rheumatoid Arthritis in the Active Stage. Method:Strictly according to follow the method of systematic review, collect completely the clinic study of TCM for Rheumatoid Arthritis in the Active Stage, choose the eligibility studies and appraise their quality, collect the data of the studies, make Meta-analyse, funnel plots and tests for heterogeneity. Result:Through collecting related articles and sieving three times, bring into 37 studies, all itemses are low quality studies.Meta-analysis results demonstrated 16 kinds of medicine prescription had statistical and clinical significance in the aspect of overall clinical efficient. Meta-analysis results of 3 kinds of medicine were stable and credible proved by the sensitive-analysis. Meta-analysis results to the improvement of IL-1 level prompt that Bisuqing- mixture has statistical and clinical significance.Conclusion: This evaluation system indicated Fengshi-No.1,Bisuqing-Mixture,Simiaowan heat-clearing-fang are is first commended heat-clearing Formula of chinese medicine to 3 therapeutic schedules for the overall clinical efficient of Rheumatoid Arthritis in the Active Stage.Bisuqing- mixture is effective to to the improvement of IL-1 level. Other further researches depended on the large sample.