Clinical Study On ACS Disease By The Method Of Supplementing QI And Activating Blood Circulation

Objective: To observe the therapeutic effect and discuss the mechanism of the Method of Supplementing Qi and Activating Blood Circulation combined with Western medicine on acute coronary syndrome (ACS) disease. Methods:60 patients with ACS were randomly divided into the control group and treatment group with 30 cases in each group. The patients of the control group were treated with routine medicine and those of the treatment group were added with traditional Chinese medicine (TCM) HuangQi injection combined with Danshen injection At the same time, conventional western medical therapy was given to the control group.4 week as one therapeutic course. The changes of clinic symptoms and signs of TCM, electrocardiogram(ECG), low density lipoprotein cholesterol (LDL-C) and high sensitive C-reactive protein (HS-CRP) of all patients were observed before and after treatment。Results: The results showed that the Method of Supplementing Qi and Activating Blood Circulation could significantly improve clinical symptoms and heart function,decrease vessel active substance, decrease inflammation and decrease blood-lipid (LDL- C) and hs-CRP,Statistics showed that the effects of treatment group were obvious better than control group's(P <0.01),The total effective rate showed by clinical symptoms and ECG were 95.2% and 76.7% in the treatment group and 74.5% and 56.7% in the control group, there was significant difference between two groups. HS-CRP and LDL- C of all patients decreased after treatment (P <0.01), but the treatment group was lower than the control group(P <0.05)and there was significant difference between two groups. The treatment group showed decreasing in the concentration of ET-1 and increasing in the concentration of NO, all that were significantlydifferent from that of the control group( P < 0. 05) . Conclusion:The Method of Supplementing Qi and Activating Blood Circulation has the function of supplementing Qi and activating blood Circulation , improving clinical symptoms , modulating endothelial function,decreasing blood-lipid and decreasing inflammation,which probably may account for the effect of stabilizing coronary atherosclerosis plaque; The effect of Combined therapy of traditional Chinese medicine and western medicine is obvious better than the only western medicine's.