| Caragana Jubata belongs to the genus Caragana of family Leguminosae. It is a shrub mainly distributed in northwest area of China. C. Jubata, of which Tibetan name is zuomaoxing, has a profound medicinal history in Tibetan traditional medicine. Its rhizome has the efficacy of promoting blood flow, reducing blood pressure and eliminating inflammation, which can be treated with plethora, hypertension, catamenia disorder for internal use while bruises and contused wound for external use. As a result of pharmacological activity screening test, C. Jubata has evident effects on anti-tumor, anti-inflammation and analgesia. Directed by bioactive screening, systematic isolation of dichloromethane and ethyl acetate extract of C. Jubata was carried out. Sixteen compounds were obtained by preparative chromatography methods of silica gel, Sephadex, Toyopearl, RP-gel, HPLC, et al. Based on UV, IR, MS and NMR, those compounds were identified as 9 isoflavones: L-Maackiain (CaJ-1), afrormosin (CaJ-2),Ψ-baptigenin (CaJ-3), 4'-hydroxy-6,7,3'-trimethoxy isoflavone (CaJ-4), 7,6'-dihydroxy-6-methoxy-3',4'-methylenedioxyisoflavone (CaJ-5), odoratin(CaJ-6), 5,4'-dihydroxy-7,3'-dimethoxyisoflavone (CaJ-7), 7,4'-di- hydroxy-3'-methoxyisoflavone (CaJ-8), 7,8,5'-trihydroxy-3'-methoxyisoflavone (CaJ-13); 3 flavones: 7,3'-dihydroxy-4'-methoxyflavone (CaJ-11), 7,4'-dihydroxy- flavone (CaJ-12), 7,3',4'-trihydroxyflavone (CaJ-15); 1 chalcone: isoliquiritigenin (CaJ-10); 2 stilbene monomers: resveratrol (CaJ-14), piceatannol (CaJ-16); 1 sterol: daucosterol (CaJ-9). CaJ-5 and CaJ-13 are new compounds, while CaJ-2, CaJ-4, CaJ-7, CaJ-10, CaJ-11, CaJ-12 and CaJ-15 are isolated from genus Caragana for the first time.
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