Effects Of Stent On Cerebral Intra-Aneurysmal Hemodynamics: Three-Dimensional Computational Fluid Dynamics Study

Objective: To explain the characters of hemodynamics in the wide neck and narrow neck cerebral aneurysms,study the effects of stent on the hemodynamic fields.To better understand the mechanism of the growth and rupture of the cerebral aneurysms, and offer some reference to the clinical management and development of new stents. Methods: Three—dimensional mathematical models were established and the temporal and spatial distribution of the velocity vector, the WSS and the pressure before and after the stent deployment were studied. Principles and methods of CFD were adopted. Results: Most hemodynamic parameters in the aneurysm with a wide neck are higher than that with a narrow neck. The location and its range of peak value are also different. The maximal velocity and WSS always located at the distal wall of the neck.The values of such parameters reduced significantly after the stent deployment.The stent porosity is a decisive factor of the degree of the influence.Conclusion: The numerical model is an available tool to analysize the hemodynamic characters of cerebral aneurysms.The deployment of stent can alter the intra—aneurysm hemodynamics effectively. Application of stents with special porosity may lead to a more effective endovascular treatment to cerebral aneurysms.