| Objective To investigate risk factors to angina and myocardial infarct, and differences of risk factors between these two types of coronary heart disease(CHD) for clinical practice, disease prevention and further research work.Methods Cross-sectional study was used to collect the information of in-patients with CHD in Tongliao City, Inner-Mongolia Province. Data were collected, including demographic, clinical characteristics, history of disease, family history of disease, blood pressure, blood fat and blood glucose(GLU). 572 angina cases and 516 myocardial infarct cases were selected as subjects to do case-only study to compare the differences of clinical characters and risk factors between angina and myocardial infarct, with angina cases being considered as the control group. 2594 healthy people were considered as the control group to do case-control study, who were selected from a hypertension study in Tongliao City, Inner-Mongolia Province. Many factors were analyzed, including demographic characteristics, blood pressure, blood fat and GLU, between cases and the control group. Software SPSS13.0 was used to process statistics analysis. Single factor and multiple factors logistic regression were used to compare the differences of risks to angina and myocardial infarct.Results The results of case-only analysis were that hospital days in myocardial infarct patients were longer than that in angina patients. The newcase proportion and fatality rate during hospitalization of myocardial infarct patients were higher than that of angina patients. Older age and hyperglycemia were the higher risks to myocardial infarct than to angina, OR(95%CI) were 1.017(1.002-1.033) and 1.889(1.341-2.661) respectively. Female had lower risks to myocardial infarct than to angina, OR(95%CI) was 0.481(0.338-0.683). The risk increased to angina with the raised level of systolic blood pressure(SBP)(χtrend2=10.645, P=0.001). When pulse pressure(PP)≥60 mmHg, PP was the higher risk to angina than to myocardial infarct(p=0.002). When GLU≥6.0 mmol/L, GLU was the higher risk to myocardial infarct than to angina (p=0.037).The results of case-control study were that older age, hypertension, hyperglycemia and hyperlipemia were risk factors to angina, OR(95%CI) were 1.081(1.068-1.094), 1.724(1.321-2.249), 3.049(2.272-4.090) and 4.658(3.593-6.038) respectively. There were dose-response relationships between angina and total cholesterol(TC), triglyceride(TG) or GLU. The risk increased to angina with the raised levels of TC or TG, the curve rose first and then fell down with the raised level of GLU. Older age, hypertension, hyperglycemia and hyperlipemia were risk factors to myocardial infarct, OR(95%CI) were 1.099(1.085-1.114), 1.183(1.051-1.331), 6.526(4.786-8.899) and 2.797(2.081-3.758) respectively. Female had lower risks to myocardial infarct than male, OR(95%CI) was 0.433 (0.320-0.586). There were dose-response relationships between myocardial infarct and TC, TG or GLU. The risk increased to myocardial infarct with the raised level of TC, the curve rose first and then fell down with the raised levels of TG or GLU.Conclusion Myocardial infarct patients had more hospital days, higher newcase proportion and higher fatality rate during hospitalization. Older age and hyperglycemia may have closer relationships with myocardial infarct than angina. Higher levels of SBP and PP may have closer relationships with angina than myocardial infarct. Female had higher risks to angina than to myocardial infarct. The risk of angina would increase with higher level of SBP. Age, hypertension, hyperglycemia and hyperlipemia were the same risk factors to angina and myocardial infarct. Male had higher risks to myocardial infarct than female. Risk increased to angina with the raised levels of TC and TG, the curve rose first and then fell down with the raised level of GLU. Risk increased to myocardial infarct with the raised level of TC, the curve rose first and then fell down with the raised levels of TG or GLU.
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