The Research On The Unilateral Adrenal Cortical Singli Adenoma And Unilateral Adrenal Multiple Adenoma Of Primary Aldosteronism

OBJECTIVE: Explore the differences of clinical manifestation,blood pressure, laboratory tests,treatment etc. between the unilateral adrenal cortical single adenoma and unilateral adrenal cortical multiple adenoma.METHODS: The clinical data of 39 cases of the unilateral adrenal cortical single adenoma and 41 cases of unilateral adrenal cortical multiple adenome from 2005 to 2007 were retrospectively analyzed. Blood pressure,clinical manifestation, laboratory tests of preoperation and postoperation ,imaging examination results,pathological outcomes were analyzed.RESULTS: The adenoma -diameter of group A (an average diameter of 2.13±0.86cm)is larger than the maximum diameter of the largest tumor in group B(an average diameter of 1.69±0.73cm)(P<0.05). Moreover,the serum potassium level of group A(an average potassium of 2.98±0.86mmol/l) is lower than group B(an average potassium of 3.54±0.76mmol/l)(P<6>.05). All patients underwent laparoscopic adrenalectomy,with no operative complication happened. After statistical analysis,blood pressure and serum potassium had improved significantly(P<0.05). CONCLUSIONS: Compared the unilateral adrenal cortical single adenoma and unilateral adrenal cortical multiple adenoma,the difference of pathology are not significant. The incidence of unilateral adrenal cortical multiple adenoma is high in the adenomatoid primary aldosteronism. Laparoscopic adrenalectomy is the best treatment of the unilateral adrenal cortical single adenoma and unilateral adrenal cortical multiple adenoma.