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Analysis Of Bone Mineral Density Of 411 Cases In Jinan City Proper

Posted on:2009-04-05Degree:MasterType:Thesis
Country:ChinaCandidate:W LiFull Text:PDF
GTID:2144360245495240Subject:Internal Medicine
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Objective:To study the changes of bone mineral density(BMD)in people of Jinan city proper and provide scientific basis for prevention and management of osteoporosis(OP).Methods:BMD of lumbar vertebrae(L2~L4),Femoral neck,Ward's triangle and trochanters of 411 cases aged 20~79 was measured by lunar Prodigy dual energy X-ray absorptiometry made in USA.They were divided into 6 groups by every ten years.All data were saved in the computer and statistical analyses were performed by SPSS 15.0 system for personal computers.Results:①The BMD peak values of lumbar vertebrae(L2~L4),femoral neck,ward's triangle and trochanters occurred in the age group 30~39 in females.BMD decreased with increasing age over 40,and considerablely decreased in age over 50.The BMD peak values that for males seen in 30~39 years old group,BMD decreased with increasing age over 40,and it slower than females.②In both sexes,the rate of accumulative loss of BMD at different sites accelerated with increasing age.The rate of accumulative loss of BMD,females: ward's triangle>lumbar vertebrae>femoral neck>trochanters.Males:ward's triangle>femoral neck>lumbar vertebrae>trochanters.The rate of accumulative loss of BMD seemed higher for females than for males.The rate of loss was increased for females after 50 years old,and that of lumbar vertebrae was 10.23%~25.90%in age over 50.Of the three sites of the hip(femoral neck,ward's triangle and trochanters)ward's triangle had highest rate of loss(17.63%~42.63%)in age over 50. The rate of accumulative loss of BMD in males was gradual,but there was also a rapid loss in age group of 60 at femoral neck,ward's triangle and trochanters.③2.5s below the peak BMD are regarded as the diagnostic criterion of osteoporosis(OP).The detecting rate of osteoporosis(OP)in ward's triangle of proximal femur was considerablely higher than that in lumbar vertebrae in males and females.The morbidity of osteoporosis was less than 6.25%in both sexes before 49 years old,and after 50 that was increased with age.Statistics according to the most significant parts of the rate of accumulative loss of BMD,the detecting rate of OP showed 18.04%~27.32%and 7.58%~9.09%for females and males over 50 years old respectively,30.85%~48.94%and 5.88%~11.76%over 60 years old. 43.18%~61.36%and 14.29%~28.57%over 70 years old.Conclusion:The investigation and prevention of osteoporosis is more important for females, especially for over 50 years old.As soon as,we should pay attention to males as well. The sensitivity of the detecting of BMD is females:ward's triangle>lumbar vertebrae>femoral neck>trochanters,males:lumbar vertebrae>ward's triangle>femoral neck>trochanters.
Keywords/Search Tags:Jinan city proper, Bone mineral density, Osteoporosis, Rate of accumulative loss, Detecting rate
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