The Study Of Superactue Cerebral Infraction Using Diffusion Tensior Imaging

Objective:To investigate superactue cerebral infraction using diffusion tensor magnetic resonance imaging(DTI).Materials and methods:10 praticipants were enrolled in this study(6 males and 4 females)with unilateral middle cerebral arterial occlusive disease,and there was no difference of the white and gray matter of the cerebrum scanned by the conventional MRI.The selective neuronal death is a well-recognized histopathologic sequel to ischemic brain damage.All partipants were examined by conventional MRI and a DTI protocol,the TE/TR:92/6000ms,matrix:128~*128,NEX:1,FOV:24,thickness:3.0mm,spacing:0.b value:400-3100s/mm~2,scanning time:2.8min.using a GESigna ExciteⅡ3.0T MR scanner.the data were postprocessed to generate FA and RAmap om the host computer by a DTI specific software.ROIs were selected on the internal capsule,head of caudate nucleus,semiovale centrum.bilateral FA,RAwere measured and compared.Results:1.1 FA of the normal ROIs and arterial occlusive ROIs in 5 regions with 9 b values,Anterial limb of internal capsule:Normal ROI:there was significant difference in each b value(P＜0.05).1.2 FA between normal ROIs and arterial occlusive ROIs in the five regions with the same b values(each b value).Anterial limb of internal capsule:there was significant difference between the normal ROIs and the occlusive ROIs(P＜0.001).Genu of internal capsule:there was significant difference between the normal ROIs and the occlusiveROIs(P＜0.05).Posterior limb of interal capsule:there was significant difference between the normal ROIs and the occlusive ROIs(P＜0.001).Semiovale centrum:there was significant difference between the normal ROIs and the occlusiveROIs(P＜0.05)2.1 RA of the normal ROIs and arterial occlusive ROIs in 5 regions with 9 b values,1)Anterial limb of internal capsule:Normal ROIs:there was significant difference in each b value(P＜0.05).2)head of caudate nucleus: Normal ROIs:there was significant difference in each b value(P＜0.001).OcclusiveROIs:there was significant difference in each b value(P＜0.05).2.2 RA between normal ROIs and arterial occlusive ROIs in the five regions with the same b value(each b value).1)Posterior limb of interal capsule:there was significant difference between the normal ROIsand the occlusive ROIs(P＜0.001).2)Semiovale centrum:there was significant difference between the normal ROIs and the occlusive ROIs(P＜0.05).3.1 ADC of the normal ROIs and arterial occlusive ROIs in 5 regions with 9 b values,1)Anterial limb of internal capsule:Normal ROIs:there was significant difference in each b value(P＜0.001).Occlusive ROIs:there was significant difference in each b value(P＜0.001).2)genu of internal capsule:Normal ROIs:there was significant difference in each b value(P＜0.001).Occlusive ROIs:there was significant difference in each b value(P＜0.001).3)posterior limb of internal capsule:Normal ROIs:there was significant difference in each b value(P＜0.001).OcclusiveROIs:,there was significant difference in each b value(P＜0.001).4)semiovale centrumNormal ROIs:there was significant difference in each b value(P＜0.001).Occlusive ROIs:there was significant difference in each b value(P＜0.001).3.2 ADC between normal ROIs and arterial occlusive ROIs in the five regions with the same b value(each b value).1)Anterial limb of internal capsule:there was significant difference between the normal ROIs and the occlusive ROIs(P＜0.05).2)Posterior limb of interal capsule:there was significant difference between the normal ROIsand the occlusive ROIs(P＜0.001).3)head of caudate nucleus:there was significant difference between the normal ROIsand the occlusive ROIs(P＜0.001).4)Semiovale centrum:there was significant difference between the normal ROIs and the occlusive ROIs(P＜0.05).Conclusion:DTI can be used to detect and quantify superactue cerebral infraction,it can provide useful information for clinicians.