The Analysis Of The Correlated Influence Factors On Neonatal Bone Mass In Kunming, Yunnan Province

Rickets is a chronic disease with unbalance between calcium and phosphorus metabolism resulting from deficience of Vitamin D in children,of which the feature is the pathological changes of skeleton resulting from abnormal calcification of the growing osteoepiphysic cartilage plate. Rickets can affect children's health,which is one of diseases that our country mainly prevented and treated. This disease easily cause pneumonia, diarrhea, anemia and other diseases easily .A very small number of cases may cause dilated cardiomyopathy , or even lead to heart failure. Although rickets is rarely life-threatening, but can cause bone deformity and affect children's physical and mental development. So the major measure of reducing rickets is early detection and prevention.The incidence of rickets trend will affect children's bone mineral density, and lead to decline of bone contants level. The current domestic and international research suggests: the value of bone mineral density in early life (children and young people) is the best indicators of forecasting the adult bone state. There are the factors of affecting bone accumulation and peak mass in the children and adolescents . The domestic research of the bone mineral density and the impact factors has make considerable progress .But so far, there are rarely the report about the current situation of the newborn bone mineral density and the research in the impact factors. Therefore it is theoretical and practical significance for early preventing rickets in children, increasing bone mass and reducing the adult osteoporosis and fractures to realize the level of neonatal bone mass and the movement character of bone mineral density and research in the relevant impact factors on bone mass and bone mineral density. It also provide the basis for the further longitudinal study of infant bone mass in the future and collect the information to the research in the development of human lifetime bones. This subject is to investigate and study the newborn bone mineral density in Kunming, analyse the related impact factors.[Objective]:In order to investigate the level of neonatal bone mass and the correlated influence factors in KunMing,Yunnan Province,this research has carried on questionnaireinvestigation to influential factors.[Method]:Bone mineral density of left midshaft tibia of 115 neonates,aged 0 to 28days,was measured with Aonuo ultrasound bone sonometer. Then the survey of its bomsituation,eating style and mother's life style,living situation during pregrance has beentaken by means of questionnaire investigation.[Result]:1.The BMD of full-term infants was significantly higher than of prematureinfants.2.No significant difference of BMD was found between the male and femaleinfants.3.The BMD of the premature infants had positive correlation with the height andweight. The BMD of the full-term infants hadn't significant correlation with the height andweight.4. The BMD of the newborn hadn't significant correlation with the mother'sage.5.The BMD of the neonates had positive correlation with the mother's milk andcalcium intake.6.No significant difference of BMD in neonates who were feeded indifferent style. 7.No significant difference of BMD in neonates who were born in differentseasons.[Conclusion]:The correlated influence factors of Bone Mineral Density in neonatal,KunMing city were respective:Gestational age,mother's milk intake and calciumsupplementation during pregnancy.