| Objective:To discuss the value of MR diffusion weighted imaging (DWI)and its diagnostic ability to differentiate benign from malignant breast lesions. Materials and Methods:53cases (66 lesions) were detected by Philips Gyroscan-NT 1.5 PT 6000 with breast coil. All the lesions were proved by pathologic results included 24malignant lesions and 42 benign lesions. DWI was done with single shot SE EPI sequence , b=0s/mm2,300 s/mm2,500s/mm2, 800 s/mm2, 1000s/mm2. Results: DWI showed benign and malignant lesions except 3 lesions. The apparent diffusion coefficient (ADC)values were (2.01±0.36)×10-3mm2/s for normal breast gland, (2.05±0.45)×10-3 mm2/s for benign lesions, and (1.41±0.37)×10-3mm2/s for malignant lesions; the 95% confidence interval were (1.86～2.16)×10-3mm2/s for normal breast. (1.91～2.19)×10-3 mm2/s for benign lesions, and (1.26～1.56)×10-3mm2/s for malignant lesions. There were significant differences among these ADC values(P<0.05).The ADC values of malignant group were lower then that of benign group(P<0.01).The ADC values of malignant group were lower then that of normal group(P<0.01).There were no statistic differences between benign group and normal group. The threshold between malignant and benign lesions was 1.542×10-3mm2/s according to ROC (receiver operator characteristic curve). The sensitivity and specificity for the threshold were83.3%and 85.7%, respectively .Conclusions: ADC value has the potential ability to differentiate benign from malignant for breast lesions. DWI could be a rout sequence to detect breast cancer. |
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