Change Trend Of Clinical Characteristics Of Aortic Dissection Over 10 Years In Urumqi

Objective To discuss the clinical epidemiology features and change trend of aortic dissection(AD). Methods Retrospective analysis of consecutive 238 patients with AD over 10 years in The First Affiliated Hospital of Xinjiang Medical University. Hospital records and prognosis were compared between two five-year periods. Results 238 cases with AD were hospitalized during the past 10 years. The mean age was 51.9±12.1. The male/female ratio was 3.67 to 1. Hypertension was present in 73.5% of all patients. Heavy smoking history was elicited in 44.1% of all the patients. TypeⅠdissection were identified in 35.3% of all the cases, typeⅡin 7.6%, and typeⅢin 57.1%. The mean age of the type A is much younger than type B. In-hospital mortality of acute type A dissection was 36.5%, acute type B dissection was 9.5%. In two five-year periods, the total number of cases increased by240%,among which type I was the fastest,increased by 360%. Changes of mean age and male/female ratio were not significant. Condusions This study provides insight into current regional profiles of AD. The number of hospitalized patients with AD is increasing dramatically. The mean age of the first-attack is much younger and the male ration is much higher than that reported by other regional researchers. In-hospital mortality of acute type A dissection is much higher than repouted by other regional researchers. These data support the urgent need for further improvement in prevention and treatment of AD.