| Objective: Nowadays, obesity and obesity related diseases have become worldwide healthy problems . The recent decade, peoples noticed that, children obesity may have influences on children development, especially on sex development and bone age. And in obese children , 99% ones were simple obesity(15). So, the relationship study of simple obesity and children development have grate meaning. The purpose of our study are 1. To explore the influence of obesity on sex development in boys, so that to guide clinical consultation. 2. To explore the influence of obesity on bone age in boys.Methods: All of the subjects were collected at the urinary surgery and endocrine clinic service. The obese children were choosed buy the judgement standard of obesity witch was given by Cole TJ(1,10) , this standard was said to be suitable for worldwide at every age or sex in childhood. The subjects who have the course of obese more than one years , no diseases that may influence weight and bone age , no hormons intake recently and were diagnosised simple obesity were entered as observed groups. Simultaneously, the ones who are healthy and have normal body weight were entered as control groups. All subjects were examined clinically buy myself, including body weight and height, testicular size, penis length and the circumference of penis atrioventricular furrow. Sex hormons and bone age were checked voluntarily. Detections of sex hormons include Follicle-stimulating hormon(FSH) , Luteinizing Hormone(LH) and Testosterone(T).Rsults: 202 subjects were involved in our study, the youngest is 5.1 years and the oldest is 14.6 years. There are 35 obese and 167 control boys, all subjects were divied into three groups by age: 5-10 years group, 10-12years group and 12-15 years group. There were 15, 11 and 9 obese ones and 65, 43 and 55 controls in every group. Serum FSH, LH and T were detected in 35 obese boys and 65 controls voluntarily. Moreover there were 17 obese boys progressed bone age examination. And the results are as follows: 1. Penis size: Penis length and atrioventricular furrow are bigger in older groups, and significant differences were obtained(P<0.05). No significant difference was observed of penis length and the circumference of penis atrioventricular furrow at the same age between obese boys and control boys(P>0.05). 2. Testicular size: Testicular size are bigger in older groups, and significant differences were obtained (P<0.05). There were no Significant differences on testicular size between obese boys and controls at the same age(P>0.05). 3. Sex hormons: Sex hormons are higher in older groups, Though there are no significant differences between the close together groups(P>0.05). No significant differences were observed on sex hormons between obese boys and controls at the same age(P>0.05). 4. Bnoe age: 17 obese boys progressed bone age examination , 11 of them are earlier than their age(64.7%), the most advanced of bone age than his age is 3.1 years, and the least advanced of bone age than his age is 0.1 year. And the bone age is earlier their age 0.6 year averagely of all, and significant difference was obtained compared to normal(P<0.05).Conclusions: 1. there are no significant difference on penis size, testicular size and sex hormons in boys between simple obese boys and normal boys. It's because of penis were buried into fat tissue, so that obese boys penis looked small. 2. Obese boys's bone age are earlier than their age, but more study should be made about the influence of earlier bone age on height in adult.
|
PDF Full Text Request