The Clinical And Angiographic Features Of Intracranial Aneurysms

To analyze the features of intracranial aneurysms, investigate the differences between ruptured and unruptured aneurysms, and evaluate the risk of rupture of unruptured aneurysms, 717 patients from Jan 2003 to Dec 2006 were analyzed. The data were characterized by female preponderance, age at admission, the proportion of multiple aneurysms, the seasonal and circadian fluctuation, vasospasm, distribution of sites, characteristic of ruptured aneurysms, symmetry of A1 segments and so on. Several features were emphasized here: (1) Relatively large number of dolichoectasia and dissection aneurysm were reported; (2) Mean max diameter in this group is obviously smaller than Western countries which may due to difference of races; hypertension doesn't influence the rupture size of aneurysms; the critical size of Chinese people maybe 3 mm; male gender and younger age have relatively high risk of vasospasm; (3) This study divide saccular aneurysms into 4 types according to morphology: multilobula, dumb bell, unilobula irregular and unilobula regular; (4) Logistic stepwise regression analysis applied to the ruptured and unruptured aneurysms identified the site, morphology, aspect ratio of aneurysm, have daughter blebs or not, patient age as 5 main independent statistically significant factors correlating with rupture; yielding one equation to assess the estimated probability of rupture. (5) If the estimated probability of rupture is high, operative risk is low, the patient is in good condition and life expectancy is more than 5 years, actively operative therapy should be proposed.