Study On The Relative Factors For Dementia After Ischemic Stroke

Objective:To examine relative factors for dementia after ischemic stroke.Methods:A total of 368consecutive patients with ischemic stroke were enrolled in this study,and 300 patients were examined with MMSE,ADL,etc during admission and 3 months after stroke to screen out one's who had cognitive impairment,and then assessed with a battery of neuropsycholgical tests.The clinical,diagnosis on dementia was based upon the 4th Edition of Diagnostic and Statistical of Manual of Mental Disorder,Revised version (DSM-â…£).VD was identified with the National Institute of Neurological Disorders and Stroke and Association International pour la Recherche et l'Enseignement en Neuroscien-ces criteria(NINDS/AIREN).Hachinski(HIS)was used to distinguish AD and VD. The group of dementia was 45 and undementia group was 255.t test and x~2 test were used to evaluate the incidence and to find the relative factors for dementia after ischemic stroke.Results:The study indicates the incidence of dementia after ischemic stroke was 15%.The patients with dementia after ischemic stroke more often had old age.low educaltional level,diabetes mellitus(OR=6.719,P=0.025),alcohol drinking history (OR=23.500 P=0.000)and stroke history(OR=5.833 P=0.040)are relative with dementia after ischemic stroke and stastically insignificant.Conclusion:Stroke increases the risk of dementia.Vascular factors play a master role in the pathogenesis of dementia after ischemic stroke.Relative factors for dementia after ischemic stroke are age,low educational level,diabetes mellitus,alcohol drinking and stroke history.