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Evaluation Of MSCTA And MSCTP For The Liver Transplantation

Posted on:2008-08-30Degree:MasterType:Thesis
Country:ChinaCandidate:H XunFull Text:PDF
GTID:2144360218956429Subject:Medical Imaging and Nuclear Medicine
Abstract/Summary:PDF Full Text Request
Objective To evaluation application of MSCTA and MSCTP technology in pre-and pro-liver transplantation.Materials and Methods 32 patients with liver transplantation were performed MSCT(multi-phase CT scanning)including 10 cases of liver cancer and 22 cases of cirrhosis with Child-Pugh C stage.In hepatic artery and portal phase vascular 3D imaging reconstruction methods include MPR,(multiple planar reconstruction MPR)MIP(maximum intensity projection),VR(volume rendering VR).MIP images were measured abdominal celiac(CA),left gastric artery(LGA),common hepatic artery(CHA),proper hepatic artery(PHA),the superior mesenteric artery(SMA)and portal vein(PV),splenic vein(SV), superior mesenteric vein(SMV)in diameter.Siemens company CT P-2007 A perfusion software to calculate the volume of hepatic arterial infusion(HAP) portal perfusion(PVP),total hepatic blood flow(TLP),and hepatic perfusion index(HAI),observed before and after liver transplantation perfusion abnormality;Evaluation of patients with cirrhosis of the CT perfusion parameters and MELD score between relevance.SSPS10.0 with data processing, hepatio artery and portal phase of the Main-related artery and its branches showed that the rate OK X2 test,compared with MIP VR reconstruction of the merits;Information using mean±standard deviation((?)±S)that the two groups were compared using a few t-test;multiple comparison with the single-factor analysis of variance(ANOVA),compared with February 2 q test P<0.05 was statistically significant. Results hepatic caocinoma and liver cirrhosis were daignoses using MSCT. Hepatic arterial vascular imaging scan can show clearly within the scope of the abdominal aorta,gastroduodenal artery,hepatic artery,the left hepatic,celiac trunk and its branches.11 cases in the hepatic disease group and 6 cases in the control group were seen hepatic aterity malformation,in Portal vascular imaging clearly showed that the portal vein system.MIP can use accurate measurement of vascular diameter abdominal aorta and portal,superior mesenteric vein and splenic vein diameter.Control group with liver cirrhosis and liver cancer artery diameter no significant difference in patients with portal hypertension and the portal vein,mesenteric vein and splenic vein diameter compared with the control group,the difference was statistically significant(P<0.05).HAP control group, the HPP,TLP and HAI respectively 31.67±11.460ml·min-1·100ml-1, 110.05±28.01ml·min-1·100ml-1,138.47±41.67ml·min-1·100ml-1,22.26±5.06%。Before transplantation and liver cirrhosis group HAP,the HPP,TLP and HAI respectively 38.85±4.09,59.77±7.97,98.63±8.83 ml·min-1·100ml-1, 39.55±4.31%and 38.25±3.54,88.63±12.36,126.88±13.22 ml·min-1·100ml-1, 30.35±3.50%;Compared with the control group,patients with liver cirrhosis and liver cancer and HAP HAI significantly higher,cirrhosis and liver cancer HPV significantly reduced cirrhosis group TLP lower P<0.05,the difference was statistically significant;HCC Group TLP slightly decreased,P>0.05,the difference was not statistically significant.Group after transplantation and liver cirrhosis group HAP,the HPP,TLP and HAI were:42.13±4.76,91.44±10.47,133.57±12.88 ml·min-1·100ml-1,31.60±2.76%and 40.25±5.06,117.63±10.39,151.88±13.12 ml·min-1·100ml-1,26.50±2.51%,Compared with the control group, after cirrhosis and liver cancer and HAP HAI significantly higher,cirrhosis group HPP lower P<0.05,the difference was statistically significant;TLP reduced cirrhosis group,liver and TLP HPP group increased slightly,P>0.05, the difference was not statistically significant.Cirrhotic group was compared with preoperative,HAP,HPP and HTP were increased significantly,HAI lower P<0.05,the difference was statistically significant.HCC group was compared with preoperative,HPP increased HAI lower,P<0.05,the difference was statistically significant.Chronic liver disease patients with end-stage liver perfusion and clinical evaluation of liver function MELD score negatively correlated,MELD and HPP(r=-0.814,p=0.000),MELD and TLP(r=-0.775, p=0.000),Note MELD score higher,portal and hepatic perfusion lower.Conclusion MSCTA is can shown the liver artery and portal vein system of the non-invasive method of checking,Joint MIP and VR application can provide more clinical liver transplant before the hepatic artery and portal vein of information,liver transplantation arteriovenous anastomoses provide for the monitoring of vascular diameter and vascular complications.CT perfusion scanning in understanding diseases caused by abnormal perfusion,and thus to understand before and after liver transplantation of the liver perfusion.Chronic liver disease patients with end-stage liver perfusion parameters and the MELD score negative correlation,for the evaluation of liver function reference.
Keywords/Search Tags:liver transplantation, Angiography, Perfusion Imaging, X-ray computer
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