The Analysis Of Pathological Change With Different Restorative Procedure To Deal With Acetabularis Cartilago Coloboma

Objective:To analysis the difference of the pathological changes with different restorative procedure to treat acetabularis catilagocoloboma.We can get the result that the cartilage that transplanted can do well to rehabilitate our acetabularis and we also get to know that the cells of cartilage that transplanted is similar with normal cartilage tissue. Curative effect of team tread with transplant cartilage is better than other teams.Methods: We can devided 18 experimental New Zealand rabbits into three teams that treat with different methods that conclude of transplanting cartilage,boring the cartilage and none disposaling.We can get the rabbits'acetabularis after two and four and eight weeks to the data of disposaling.We then compared the difference of the pathological changes with different restorative procedure to treat acetabularis catilagocoloboma.Results: 1.2 weeks afrer different disposaling:Naked eyes specimen is clear that the comparision team fiber tissue has no obvious hyperplasia, the cartilage defection has no obvious fiber tissue to overlay.Articular bursa can be seen with slight hyperplasia and conglutination.The ability of walking owed by that experimental rabbits depressedB?The Naked eyes specimen of acetabulariscartilage transplant team can be seen that fiber tissue partly to overlay the cartilage defection. Its height is lower compared to normal cartilage tissue, the color had difference with normal tissue, combining with normal cartilage tissue around not very close, bring about easily. Articular bursa can be not seen with obvious hyperplasia and conglutination.The ability of walking owed by that experimental rabbits depressed compared with normal conditionB?The pathology change observed by microscope as follows:The comparision team fiber tissue fills the place of acebulariscartilage incompletely, with big difference compared to normal tissue, without the cartilage cell and cartilage quality to secrete. The team disposaled with boring the cartilage can be seen with fiber tissue fills the place of acebulariscartilage incompletely, with smaller difference than the comparision team, without the cartilage cell and cartilage quality to secrete. The team transplant acebulariscartilage can be seen with fiber tissue fills the place of acebulariscartilage completely, with small difference with normal tissue, and can find the cartilage cell and cartilage to secrete.2. 4weeks afrer different disposaling:Naked eyes specimen is clear that the comparision team fiber tissue has slight hyperplasia, the cartilage defection has no obvious fiber tissue to overlay.Articular bursa can be seen with slight aggravate hyperplasia and conglutination.The ability of walking owed by that experimental rabbits depressed more.The Naked eyes specimen of acetabulariscartilage transplant team can be seen that tissue like cartilage completely to overlay the cartilage defection. Its height has little difference compared to normal cartilage tissue, the color had difference with normal tissue, combining with normal cartilage tissue around close, bring about uneasily. Articular bursa can be not seen with obvious hyperplasia and conglutination.The ability of walking owed by that experimental rabbits depressed compared with normal conditionB?The pathology change observed by microscope as follows:The comparision team fiber tissue fills the place of acebulariscartilage incompletely, with big difference compared to normal tissue, without the cartilage cell and cartilage quality to secrete. The team disposaled with boring the cartilage can be seen with cells of cartilage tissue fills the place of acebulariscartilage completely but different with normal tissue and can not find the cartilage cell and cartilage to secrete.. The team transplant acebulariscartilage can be seen with cartilage tissue fills the place of acebulariscartilage completely, with small difference with normal tissue, and can find the cartilage cell and cartilage to secrete.3.8weeks afrer different disposaling:Naked eyes specimen is clear that the comparision team fiber tissue has slight hyperplasia, the cartilage defection has no obvious fiber tissue to overlay.Articular bursa can be seen with more aggravate hyperplasia and conglutination.The ability of walking owed by that experimental rabbits depressed more compared to before.The Naked eyes specimen of acetabulariscartilage transplant team can be seen that cartilage tissue to overlay the cartilage defection. Its height has more little difference compared to normal cartilage tissue, the color had little difference with normal tissue, combining with normal cartilage tissue around close, bring about uneasily. Articular bursa can be not seen with obvious hyperplasia and conglutination.The ability of walking owed by that experimental rabbits depressed compared with normal conditionB?The pathology change observed by microscope as follows:The comparision team fiber tissue fills the place of acebulariscartilage incompletely, with big difference compared to normal tissue, without the cartilage cell and cartilage quality to secrete. The team disposaled with boring the cartilage can be seen with cells of cartilage tissue fills the place of acebulariscartilage completely but different with normal tissue and can not find the cartilage cell and cartilage to secrete.The team transplant acebulariscartilage can be seen with cartilage tissue fills the place of acebulariscartilage completely, with more little difference with normal tissue, and can find the cartilage cell and cartilage to secrete.Conclusion: 1.three kinds of dissimilarity repair methods can be different degree repair at the different stage.2.Pathology chang at 2nd-week,4th-week,8th-week is greatB?3. Curative effect of team tread with transplanted acebulariscartilage is best, Curative effect of team of boring cartilage is better than compared team.