The 26 Cases Of Diabetic Liver Disease Clinical Evaluation

Objective:To study the Diabetic liver disease(DLD)in the pathogenesis, clinical and pathological features,diagnosis and treatment.Methods:the group of 26 cases of the DLD,diabetes transcribed diet,intensive insulin therapy, Observation of the patients before and after treatment and clinical manifestations of various biochemical parameters,B and liver biopsy wearing,super-and the non-diabetics with liver pathology wear 10 cases for comparison.Results:the DLD groups:26 patients with intensive insulin therapy after a course of treatment,18 cases of diabetic symptoms disappeared,6 distension,loss of appetite and three cases of liver pain is relieved,and five cases were stained sclera dissipated,15 cases of liver large and their 6 were associated with splenomegaly treatment regimen after a review of the liver and spleen B had different narrow-,8 cases of liver caught change shape and slightly harder texture soft,reviewed 17 cases of liver function to normal.Treatment of two or more cycles,liver function returned to normal.One patient hepatosplenomegaly, and admission is a little more than three symptoms associated with the stomach, loss of appetite,liver pain,anorak with a number of spider angioma,sclera mild yellow,liver large subcostal oblique 8cm,shape and slightly harder texture,and the spleen can be lateral;B said diffuse liver damage,no lesions,said esophageal endoscopy vein exposed,super-After three courses(only three of the cases persist course)B liver and spleen after a review of various magnitudes narrow-review esophageal endoscopy revealed vein disappeared.The DLD group shows special pathological changes:glycogen deposition,nuclear glycogen empty in 23 cases,Hepatocyte steatosis 16;Hepatocyte balloon-like variable 16;Interstitial fibrosis six cases;non-diabetic group transhepatic liver pathology had no nuclear glycogen empty cytoplasm liver glycogen DM group less fatty degeneration 2,balloon-like change one cases,cell change for liver disease and diabetes group basically the same.Conclusion:Diabetic patients with chronic liver condition is high blood sugar diabetes caused liver injury the major factor,Diabetics with poorly controlled diabetes caused liver injury can lead to abnormal liver function,also accompanied hepatomegaly;Liver biopsy results to glycogen deposition and fat deposits,and the nucleus is empty glycogen most characteristic changes Diabetes is a major disease of the liver diagnosis.Low-dose insulin infusion treatment of diabetic liver,not only rapid control of blood glucose,insulin can make up faster portal,portal and maintain high levels of insulin,glucose metabolism disorders correct promote glycogen and fat deposition,reduce the swelling of liver cells,improve liver injury,liver function was improved,hepatomegaly reduce or even back to normal.