Macular Volume And MacularNeurosensory Retinal Thickness In Unilateral High Myopia Amblyopia Of Children

Purpose To study the macular volume and thickness of the unilateral high myopia amblyopia of children.To investigate whether the morphology of macula changes or not in the unilateral high myopia amblyopia.Methods 21 unilateral high myopia amblyopia cases (21 eyes), 17 normal cases (34 eyes) and 17 high myopia which the corrected visual acurity was normal cases (30 eyes) were tested by Optical Coherence Tomography(OCT) in the posterior pole of retina.We classified the macular map into two parts:the macula center(B1) and the latero-macular(B2～B9) .We measured the macular volume and thickness of each regions. The relative macular volume and thickness of high myopia amblyopia were compared with those of fellow eyes,normal eyes and high myopia which the corrected visual acurity was normal respectively. Finally, the results were analyzed statistically.Results In high myopia amblyopia, the total macular volume was 6．419±0．408mm~3 and the mean macular RNE thickness was 225．18±10．33μm.The macular volume and the RNE thickness were no statistically significant differences in the macula center(B1) between the four groups(p>0．05) . But the macular volume and the RNE thickness in the latero-macular(B2～B9) in high myopia amblyopia were smaller, it showed statistically differences when compared with fellow eyes,normal eyes(p < 0．05) and no significant differences when compared with high myopia which the corrected visual acurity was normal(p>0．05) . The macular volume and the RNE thickness decreased with axises oculi in high myopia amblyopia and high myopia which the corrected visual acuity are normal, there were inverse linear correlation between the macular volume,thickness and axises oculi (p < 0．05) .Conclusions 1,Both the macular volume and the RNE thickness showed the significant differences between unilateral high myopia amblyopia and fellow eyes,normal eyes,however there is no significant differences compared with the high myopia eyes which the corrected visual acuity was normal.2,The macular volume and the RNE thickness in unilateral high myopia amblyopia and high myopia with normal corrected visual acurity showed the negative correlation with axises oculi,which suggested that the change of the macular volume and the RNE thickness in unilateral high myopia amblyopia might have the relationship with the change of axises oculi.However, this kind of chang might not be the reason which caused the decline of visual acurity in amblyopia children.