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Comparative Study Between MDCT Staging With Pathological Staging And Classification Of Syndrome Differentiation Of Thoracic Esophageal Cancer

Posted on:2008-02-24Degree:MasterType:Thesis
Country:ChinaCandidate:Y Q TaoFull Text:PDF
GTID:2144360215981484Subject:Traditional Chinese Medicine
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ObjectiveTo compare the multi-detector computed tomography (MDCT) staging,pathological staging and typing according to syndrome differentiation ofesophageal cancer, to evaluate the values of MDCT scanning in theclinical staging of esophageal cancer and the correlation between MDCTimaging performance, staging and typing according to syndromedifferentiation.Material and MethodsMDCT enhancement scanning and typing according to syndromedifferentiation by traditional chinese medicine (TCM) were performedpreoperatively in 98 patients with diagnosed esophageal cancer. MDCTimaging results were compared with the resected specimens ofhistopathologic examination and typing according to syndromedifferentiation.ResultsThe accuracy of MDCT was 72.4%(71/98) in T staging, and compared withpostoperative pathological results kappa coefficient is 0.505 (P<0.01);The sensitivity, specificity and accuracy of MDCT in N staging were48.2%(109/226), 99.7%(2411/2418) and 95.3%(2520/2644), and compared withpostoperative pathological results kappa coefficient is 0.615 (P<0.01); The staging by MDCT were significantly accordant with the typingaccording to syndrome differentiation by TCM (x~2=34.2450, P<0.01); In thispattern's patients of phlegm-qi obstructing each other, MDCT imagesdemonstrated thickening esophageal wall which were significantly thinnercompared to the other pattern types. There was no significant differencein the length of lesion esophageal among the various types.Conclusion1. A high agreement was found between preoperative MDCT staging andpostoperative pathological staging of esophageal cancer. PreoperativeMDCT staging has important clinical value.2. There were significantly correlations between MDCT staging andtyping according to syndrome differentiation in TCM of esophageal cancer,thickening of esophageal wall that demonstrated in MDCT image can beused as an objective index for typing according to syndromedifferentiation.
Keywords/Search Tags:Esophageal Neoplasms, X-ray computed tomography, Syndrome differ classification, Pathologic processes
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