The Study Of Relationship Between Infection Burden And Coronary Atherosclerosis

Objective To evaluate the relationship among infection burden, coronary atherosclerosis and the severity of atherosclerosis.Methods Ninety patients underwent coronary angiography in Jiangsu Province People Hospital in 2004. Seropositivity of cytomegalovirus, helicobacter pylori, chlamydia pneumonia, influenza A virus, herpesviruses-1 were determined by ELISA. According to the infection burden, the patients were divided into 3 group: group 1, pathogen≤2; group 2, pathogen=3; group 3, pathogen≥4.Results The ratio of coronary atherosclerosis was neither associated with infection burden significantly (P＞0.05), nor increased with the increasing of the pathogen. The prevalence of atherosclerosis was 84.~16%,81.6% and 73.9%. Neither the severity of atherosclerosis was significantly associated with infection burden nor the degree of the severity was increased with the increasing of infection burden.Conclusion The present study does not suggest that the prevalence of atherosclerosis is associated with infection burden and increased with the increasing of infection burden. The severity of atherosclerosis does not associat with infection burden.