Study On Quality Standard Of Fufang Tuoying Mahuang Chajian Capsules

Bronchial asthma severely threatens the health of mankind with high morbidity. Fufang Tuoying Mahuang Chajian Tablets as a complicated preparation were used for the treatment of the chronic bronchial asthma mainly,including fenitoina sodica 50mg;theophylline 12.5mg;theobromine 12.5mg;caffeine 7.5mg;ephedrine hydrochloridum 5mg and belladonna fluid extract 0.0009ml respectively per capsule.Fufang Tuoying Mahuang Chajian Tablets have been proved to be a effective drug by clinical use for many years. And it is welcomed by doctors and patients. Our group has finished the study of quality standard on Fufang Tuoying Mahuang Chajian Tablets.Beacause Tablets have many disadvantages,such as the complicated production process and lower dissolution,however capsules can overcome above disadvantages.On the side, Capsules also could cover the bad smell of drug.In this paper,the dissolution and the content of Fufang Tuoying Mahuang Chajian capsules were studied systemicly. The results show that the dissolution of capsules was improved obviously comparing with the Tablets.A reverse phase high performance liquid chromatography assay was carried out for the determination of fenitoina sodica,Other four active components in capsules were quantified simultaneously by aother mobile phase.The ranges of their equitabilities were defined.In a word,this method is rapid,accurate,and suitable for the quality control of the Fufang Tuoying Mahuang Chajian capsules.