Clinical Analysis On Patients With Severe Traumatic Brain Injury Administrated With Hyperbaric Oxygen And Naloxone At The Early Stage

Objective: At present, it was already proved that hyperbaric oxygen has better actionto severe traumatic brain injury, Naloxone can reduce the level of opioid peptide contentin plasma and cerebrospinal fluid of patients with traumatic brain injury. To study theeffectiveness of Hyperbaric oxygen and Naloxone at the early stage treatment onpatients with severe traumatic brain injury is our objective.Method: 90 patients with severe traumatic brain injury were randomly divided intotwo groups. A group was administrated with Hyperbaric oxygen and Naloxone at the earlystage. B group was administrated with Hyperbaric oxygen at the early stage.Result: The fluctuation of vital signs in the first 3 days was smoother in A group thanin B group,including arrhythmia and abnormal respiration. CT scanning and lumbarpuncture showed that the severity of brain edema and increase of intracranial pressurewas less remarkable in A group after treatment for one week. More patients revived in Agroup than in B group in 7 days accompanied by higher recovery rate and lower disabilityafter 3 months.Conclusion: Hyperbaric oxygen and Naloxone at the early stage treatment onpatients with severe traumatic brain injury can relieve traumatic brain edema and improvethe recovery of coma and reduce the disability in severe brain injuries.