Studies On Chemical Constitudents Of Gueldenstaedita Multiflora Bge. And Delphinium Grandiflorum L.

In this M.D thesis,chemical constituents of Gueldenstaedita multiflora Bge.,Delphinium grandiflorum L.had been studied.The compounds were isolated by means of silica gel column chromatography(CC),short column chromatography by reduce pressure and recrystallization et al.The structures of these compounds were determined by chemical transformations and spectroscopic identification including IR,EI-MS,GC-MS,¹HNMR,¹³CNMR,DEPT,¹H-¹H COSY,gHMQC,gHMBC. From the Gueldenstaedita multiflora Bge.,the identified seven compounds were: loliolide(A₁),Liexiangdujuanineâ… (B₁),Friedelinol(B₂),Friedelin(B₃), Stigmast-4-en-3-one(B₄),A'-Neogammacer-22(29)-en-3β-ol,acetate(B₅),β-sitosterol(B₆),Compounds A₁,B₁～B₆ were obtained from this plant for the frist time and compound A₁ was water-solubility,the others were nonwater-solubility。From the Delphinium grandiflorum L.,the identifyied thirteen compounds were: grandiflorineâ…¢(Y₁),isotalatizidine(Y₂),14-O-methylisotalatizidine(Y₃), 4',7-dimethoxy-5-hydroxyflavone(Y4),anthranoyllycoctonin(Y₅),deoxylycoctonine (Y₆),umbrosine(Y₇),N-cinnamoyl-2-phenylethylamine(Y₈),methyllycaconitine (Y₉),delcosine(Y₁₀),delsoline(Y₁₁),grandiflorine(Y₁₂),lycoctonin(Y₁₃) and a amide alkaloid(Y₁₄).Above all of them,compound grandiflorineâ…¢(Y₁)was a new diterpene alkaloid,and compounds Y₂～Y₈ were obtained from this plant for the frist time.The part of soluble chemical constituents and its volatile oil constituents of Gueldenstaedita multiflora Bge.have not been reported previously.Besides,The classification,chemical constituents and pharmacological activities of Diding were summarized in the first part.