Pharmaceutical Studies On Jiakang Granule

Hyperthyroidism is a sort of familiar organ specifical autoimmune disease in endocrine illness,and that is directly related to inheritance and immune factor. According to the statistics,there are about 14 millions hyperthyroidism patients in China.The morbidity is growing and has the severe impact on the life quality of the average people. We had changed decoction to granule for taking medicine conveniently and enhancing stability of drugs. This subject includes the preparation and quality stardard of JiaKang granule.During the studies of the preparation,there are four parts involving studies on extraction and inclusion of volatile oil from prunella vulgaris,bupleurum root and turmeric,studies on alcohol extraction,water extraction , studies on decocted with water and deposited with alcohol by the orthogonal test.The method of oil inclusion reported by current documents is proved.In the researches of quality standard, bupleurum root, curcuma root and forsythia suspensa have been tested to exist by TLC.The determination result of ursolic acid in the granule is 0.174 mg·g^-1.The stability of the granule character has proved the primary stability research.