The Clinical Analysis Of 148 Adult Epilepsy

Objective: to investigate the characteristics of the adult epilepsy, to obtain some knowledge about the etiological factors, auxiliary examination, seizure type and drug therapy.Method: 148 patients (age>=18years) who were diagnosed epilepsy in QiluHospital of Shandong University from February 2006 to February 2007 were enrolled in the study. The detailed information about these patients were collected and analyzed.Results: (1) Among 148 patients, 52 patients were diagnosed as symptomaticepilepsy, and the rate of symptomatic epilepsy grows as the age of the patients grows. (2) The main etiologies of adult epilepsy are infection of CNS, CVD, cerebral trauma and so on. (3) 120 patients do the EEG examination and 85 patients have positive finding; 91 patients have CT examination and 40 patients have positive finding; 25 patients have MRI examination and 12 patients have positive finding. (4) GTCS,CPS,SPS are the main seizure types of adult epilepsy.(5)PHT,CBZ,VPA are the most commonly used antiepileptic drugs in adult epilepsy, the drug efficiency is different in symptomatic epilepsy and non-symptomatic epilepsy.(6)New antiepileptic drugs such as TPM,LTG,OXC are efficient.Conclusion: (1) The rate of the symptomatic epilepsy grows as the age grows.(2) Infection of the CNS,CVD,trauma,tumor are the main abnormal findings.(3) CT/MRI should be carried in adult epileptic patients.(4) GTCS,CPS,SPS are the main seizure types in adult epilepsy.(5) The efficiency of the drug therapy is better in non-symptomatic epilepsy when compared with symptomatic epilepsy.(6) New antiepileptic drugs are efficient.