Experimental Study Of Hydroxyapatite/ultra-high Molecular Weight Polyethylene And High-density Porous Polyethylene Used For Reconstruction Of Orbital Of Rabbits

Objective To compare the biocompatible and osteconduction behavior of the high-density porous polyethylene and hydroxyapatite /ultra-high molecular weight polyethylene.Methods Osteoectomy of the upper orbital rim was performed on 24 adult new Zealand rabbits .The animals were randomly divided into 3 groups with 8 of each. The hydroxyapatite/ultra-high molecular weight polyethylene , high-density porous polyethylene was implanted to the upper orbital defect of the animal in respective group. Animals were sacrificed at 1, 2, 4, 8weeks.Histopathologie sections of the implants were evaluated and compared with light and transmission electron microscopy study. Alkaline phosphatase (ALP) and Osteocalcin(OC) in the HDPE and hydroxyapatite/ultra-high molecular weight polyethylene was also checked.Result During the experimental period of 8 weeks, there was no implants extrusion or displacement . Fibrous tissue and new vessels grows into HDPE elder and obviously than hydroxyapatite/ultra-high molecular weight polyethylene. Alkali phosphatase and osteocalcin contents has...