Screening Of Serum Glucose And Clinical Study In Patients With Coronary Artery Disease.

[Background] Diabetes is coronary heart disease risk equivalent, which was put forward firstly by Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) in 2001. This concept has been accepted by most of people. The prevalence of abnormal glucose metabolism is high in patients with coronary artery disease(CAD). The coronary artery disease, with diabetes or impaired glucose regulation (IGR) , is associated with increased mortality of cardiovascular disease and other reasons. People have put more attention to the patients with CAD and diabetes, but have not to the patients with CAD and impaired glucose tolerance (IGT) or newly diabetes . [Objective] To screen the glucose metabolism status and do clinical study in patients with CAD .[Methods] All inpatients with CAD in cardiology department of our hospital were consecutively recruited from Sep 1, 2005 to Oct 3 1. 2005. A total of 108 patients with CAD were included in the study. The clinical information was compiled. Among all the patients, 27 ones had diabetes mellitus (DM ) history and 10 ones were diagnosed DM through fasting plasma glucose(FPG) . The other 71 patients undiagnosed DM would perform simplified oral glucose tolerance test (OGTT) to characterize the glucose metabolism status. [Results] 11 patients were newly diagnosed DM through OGTT. The prevalences of patients with DM and IGR were 44.4% and 24. 1% in inpatient with CAD, respectively. The total prevalence of abnormal glucose metabolism was 68.5 %. Without the use of OGTT, 80.8% impaired glucose regulation and 23.4% DM would remain undiagnosed by FPG detection alone. The 2h glycemia of OGTT and serum cholesterol and Waist-Hip Ratio(WHR) are interrelated.[Conclusion ] The frequency of disturbed glucose metabolism is considerably high in inpatients with CAD. Simplified OGTT easily discloses the glucometabelic status and should be as a routine procedure in the diagnosis of such patients, especially in patients with high serum cholesterol and high WHR. [Background] Diabetes is a proven risk factor for stroke, with a two- to threefold increased risk for diabetic patients compared with nondiabetic patients. The prevalence of abnormal glucose metabolism is high in patients with cerebrovascular disease (CVD). The cerebrovascular disease, with diabetes or impaired glucose regulation (IGR) , is associated with increased mortality of cardiovascular disease and other reasons. People have put more attention to the patients with CVD and diabetes, but have not to the patients with CVD and impaired glucose tolerance (IGT) or newly diabetes. [Objective] To screen the glucose metabolism status and do clinical study in patients with CVD .[Methods] All inpatients with CVD in neurology department of our hospital were consecutively recruited from Sep1, 2005 to Oct 31.2005. A total of 141 patients with CVD were included in the study. The clinical information was compiled. Among all the patients, 33 ones had diabetes mellitus (DM) history and 14 ones were diagnosed DM through fasting plasma glucose(FPG) . The other 94 patients undiagnosed DM would perform simplified oral glucose tolerance test (OGTT) to characterize the glucose metabolism status.[Results] 20 patients were newly diagnosed DM through OGTT. The prevalences of patients with DM and impaired glucose regulation were 47.5% and 34.8% in inpatient with CVD, respectively. The total prevalence of abnormal glucose metabolism was 82.3%. Without the use of OGTT, 67.3%impaired glucose regulation and 29.9%DM would remain undiagnosed by FPG detection alone. The 2h glycemia of OGTT and fast blood glucose (FBG) are interrelated.[Conclusion] The frequency of disturbed glucose metabolism is considerably high in inpatients with CVD. Simplified OGTT easily discloses the glucometabelic status and should be as a routine procedure in the diagnosis of such patients, especially in patients with high FBG.