The Analysis Of Quality Of Life In Patients With Obstructive Sleep Apnea Hypopnea Syndrome

Objective To evaluate the difference of each index ,such as quality of life ,between the patients with obstructive sleep apnea hypopnea syndrome(OSAHS) and the patients with simple snoring; and to analyse the correlation factor and the influencing factor of quality of life in the patients with OSAHS, in order to offer reliable evaluation methods.Methods 45 patients because of snoring were monitored by PSG in my hospital without any treatment in the past ,and they had no diseases which could seriously influence the sleep mental health and quality of life .Use the Calgary sleep apnea quality of life questionnaire and Epworth sleepiness scale(ESS) to evaluate the quality of life and excessive daytime sleepiness(EDS),compare the difference of the Calgary sleep apnea quality of life index(SAQLI) EDS body mass index(BMI) neck collar abdominal circumference sleep structure breathing chaos and so on between the patients with OSAHS and simple snoring. Use the pearson correlation to analyse the dependability among each index in patients with OSAHS. Use the multiple gradual regressive analysis to approach the influencing factor for quality of life in patients with OSAHS.Results1 Compare each index between the patients with OSAHS and simple snoring. The mean SAQLI I in patients with OSAHS is 4.38±0.87,daily functioning is 4.41 ± 1.10,social interactions is 5.17±0.75,emotional functioning is 5.08 ± 0.58,symptoms is 2.86±1.37, the mean SAQLI I in patients with simple snoring is 5.93±0.16, daily functioning is 5.96±0.33,social interactions is 5.94±0.37,emotional functioning is 5.95±0.25,symptoms is 5.87±0.21,there was significant deviation between them (P< 0.01) ;in the patients with OSAHS ,BMI is 28.70±3.31 kg/m~2 ,neck collar is 41.36±3.27 cm, abdominal circumference is 102.93 ±10.63 cm, EDS is 15.10±4.59, S1+S2(%) is 80.43 ± 5.86, S3±S4(%) is 10.48 ± 3.46, REM(%) is 9.09 ± 5.65,the lowest blood oxygen is 70.50 ±11.52,the mean blood oxygen is 92.22±4.55,in the patients with simple snoring, BMI is 24.81 ±2.10 kg/m~2 ,neck collar is 36.17± 3.08cm, abdominal circumference is 94.46±6.56 cm, EDS is 5.91 ±2.31, S1±S2(%) is 67.00±9.17, S3+S4(%) is 15.63 ±4.91, REM(%) is17.37±5.77,the lowest blood oxygen is 89.33±2.87,the mean blood oxygen is 96.05 ±1.20, there was significant deviation between them (P<0.01) .2 The correlation analysis between SAQLI every part and each index in patients with OSAHS. There was significant negative correlation between SAQLI social interactions emotional functioning symptoms and EDS, the results as follow: SAQLI(r=-0.363, P < 0.05),social interactions(r=-0.427, P < 0.05), emotional functioning(r=-0.383, P < 0.05) symptoms(r=-0.362, P < 0.05); there was no significant correlation between SAQLI each part and BMI neck collar abdominal circumference PSG parameter.3 The correlation analysis between EDS and each index in patients with OSAHS. There was significant positive correlation between EDS and BMI neck collar abdominal circumference AHI, significant negative correlation between EDS and the lowest blood oxygen the mean blood oxygen, the results as follow: BMI(r=0.370, P< 0.05), neck collar (r=0.444, P < 0.05), abdominal circumference(r=0.432, P < 0.05),AHI (r=0.611, P<0.01), the lowest blood oxygen( r=-0.546, P<0.01), the mean blood oxygen( r=-0.564, P < 0.01).4 The correlation analysis between AHI and each index in patients with OSAHS. There was significant positive correlation between AHI and BMI neck collar abdominal circumference, the results as follow: BMI(r=0.583, P < 0.01), neck coilar( r=0.741, P < 0.01), abdominal circumference( r=0.496, P < 0.01).5 Use the multiple gradual regressive analysis to analyse the influencing factor for quality of life in patients with OSAHS,EDS is influencing factor for SAQLI and social interactions emotional functioning symptoms the results as follow: SAQLI(R~2=0.132, P < 0.05),social interactions(R~2=0.183 , P < 0.05), emotional functioning(R~2=0.171, P<0.05), symptoms(R~2=0.167, P<0.05).Conclusions1 The SAQLI and each part in patients with OSAHS are lower than simple snoring, OSAHS can cut down the quality of life; The BMI neck collar abdominal circumference in patients with OSAHS are higher than simple snoring, obesity is the characteristic of patients with OSAHS and the degree correlates closely to the pathogenetic condition;the patients in OSAHS have evident sleep structure and breath confused.2 The descending quality of life in OSAHS correlates closely to EDS, and does not correlate to AHI BMI neck collar abdominal circumference and the parameter of PSG..3 In patients with OSAHS,there was significant positive correlation between EDS and BMI neck collar abdominal circumference AHI, significant negative correlation between EDS and the lowest blood oxygen the mean blood oxygen, obesity sleep structure and breath confused correlate closely to the EDS.4 In patients with OSAHS,EDS is the independent predicting factor for SAQLI social interactions emotional functioning symptoms. In patients with OSAHS, EDS was the influencing factor for the quality of life.