| Objective To compare the clinlic effect of both side laser in situ keratomileusis (B. S. L) with laser epithelial keratomileusis (LASEK) for the correction of high myopia with thinner central corneal thickness.Methods To chose 68 cases (130 eyes) of high myopia, including 31 male cases (59 eyes), 37 female cases (71 eyes),who were between 18 to 35 years old, with preoperative myopia -10.67±2.19D, astigmatic errors -1.02±0.88D. The central corneal thickness of those cases was 516.23 ±22.72μm.The best corrected visual acuity (BCVA) before operation was all 1.0. These 68 cases (130 eyes) were randomly assigned as B. S. L group : 27 cases (52 eyes) including 15 male cases (29 eyes), 12 female cases (23 eyes), whose average age was 30.2 years old, with preoperative myopia -10.88±1.71D, astigmatic errors -0.99±0.97D, the central corneal thickness 503.88±13.99μm; LASEK group :41 cases (78 eyes) including 16 male cases (30 eyes), 25 female cases (48 eyes),whose average age was 26.7 years old, with preoperative myopia -10.53± 2.46D, astigmatic errors -0.98±0.88D, the central corneal thickness 491.03±25.89μm. Patients from both groups were followed postoperatively for more than 6 months, whose symptoms, visual acuity, refractive status and corneal complications were observed after surgery at 1 day, 2 weeks, 1 month, 3 months and 6 months. Results At 1 day, There was statistically significant difference in the refraction of spherical and cylindrical powers between B. S. L group... |