Studies On The Active Constituents From Leaves Of Syringa Oblata Lindl.

Syringa oblata LindL whose English name is Early lilac, is one species of Oleaceae families. There are 25 species in the Syringa genus all around the world, and they distribute mainly in the temperate zone of Asia area and the south-east of Europe. As a well known ornamental and horticultural plant, Syringa oblata Lindl. can cleanse air and be used as an indicator of the state of sulphur pollution.The taste of leaves of this plant is bitter strongly, and whose nature character is cold. As one of traditional Chinese folk herbs, it has been used to diminish inflammation, to treat the tumefaction, ulcer , putrescence , toothache , acute icterohepatitis and bacteroidal diarrhea.Recently, the pharmacological functions of Syringa oblata IindL have been studied by many scholars, while, the reports on the active constituents and their structures of this plant were less quantum correspondingly.In this thesis, the study on the chemical constituents from 75% EtOH soluble fraction of leaves of Syringa oblata IindL were carried out. With column chromatographies and fifteen compounds were obtained and purified. By means of spectroscopic analysis and physico-chemical properties, eleven of them were identified as Syringaresine( I ), 3,4:3',4'-bis(methylene-dioxy)-9'-hydroxyl-lignane-9-methyl-O-β-D-glucopyranoside(II), syringopicroside( III ), 2-furancarboxylic acid( IV ), 3,4-dihydroxybenzoic acid( V ), mannitol( VI ), cyclohexane-l,2,3,4,5,6-hexaol( VII ), succinic acid( VI ), p-hydroxyphenylethyl alcohol(IX), β-sitosterol( X), formononetin (XI). Among them Compound II was a new compound, and VII were isolated from this genus for the first time.