| Objective To investigate the role of interlin-1 β (IL-1 β ) in the second window of protection (SWOP) of renal ischemic preconditioning(IPC) against cold ischemia/reperfusion (I/R) injury in rats.Methods Forty eight SD rats were randomly assigned to four groups: normal (A), sham-operation(B), control(C), experimental group(D). All the animals were anesthetized with Chloral Hydrate (0.3ml/100g). In group C, after libing the left renal pedicle 24 hours, removed the right kidney. Cold ischemia reperfusion was performed as fellows: ①Perfusing left kidney: after resected the right kidney of the rat, a pipe was put in the remainder right renal artery to perfuse the left kidney. The perfusion flowed out of cava inferior through remainder right renal vein. The blood vessels of left kidney were clipped after cold perfusion.②Cold ischemic conservancy: the operation table was leant to left side, and the left kidney was taken out of abdominal cavity then stored in a cold bag which was full of ice and water, but the vessels of that were intact. ③...
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