The Research On LPS-TLR₄-NF-kappaB Pathway In The CDZM Of The Immunology Activity

Background:Since the application of antibiotics, people thought generally that the infectious diseases were mainly decided by the mutual functions between the antibiotics and the germs, neglected the vital role of the immunity mechanism in human body to kill the bacterium. However the practice indicated that the effective treatment must have the participation of the integrity organism defense mechanism. The defense function is playing a vital role on the infectious diseases. The antibiotics function is not the sole function from medicine to the bacterium, but a complex process which among the antibiotics, organism and the disease germ.There are some certain material of the antibiotics immunology activity, most ofthese research is Cefodizime and Cefpimizole and CDZM (business name, is GAODE) is the richest. Some research indicated that, CDZM has the obvious immunology activity, but the present research is almost the clinical effect observation, it is at the outset stage in the research of its mechanism.