Experimental Research Of The Effects Of Metabolic Syndrome Compositions On Pig Kidney Epidermis Cells

The key issue of metabolic syndrome is cardiovascular and cerebral vessel events caused by macrovascular damages. There are many researches about the major compositions of this syndrome, such as hyperglycemia, hypertension, and hyperlipidemia, etc, and relating issues such as the effect of insulin on vascular endothelial cell and smooth muscle cell. However, the study of kidney function in metabolic syndrome is rare, as well as the role of kidney in the pathogenesis of metabolic syndrome. Therefore, the study that how renal tubular epithelial cells are affected by some metabolic syndrome compositions is important to thorough understanding the pathogenesis of metabolic syndrome and its impact on kidney functions. This study focused on how pig's renal tubular epithelial cell strain was affected by glucose, uric acid, and insulin with cell culture and molecular biology methods, to explore...