Degradation Of Acellular Porcine Aorta Valve

Nowadays,current options of surgical heart valve replacement comprising of mechanical or biological prostheses substantially are the preferred replacement device in our clinical. Unfortunately, there are limitations as to the long term benefits of clinically available valve prostheses. Mechanical valves are associated with a significant risk of thromboembolism, and biological valves suffer from structural dysfunction because of calcification and progressive tissue deterioration. Contemporary clinically available valve prostheses basically represent nonviable structures and lack the potential to grow, to repair, or to remodel. Of particular importance to the pediarric population, homografts and all other currently available conduits and valves have no ability to grow. Tissue engineering is an evolving science joining engineering and biology in an attempt to develop replacement tissue, and represents a novel scientific concept to overcome these limitations aiming at in vitro fabrication of living heart valves with a thromboresistant surface and a viable interstitium with repair and remodeling capabilities. At the present time, in the fields of studying artificial heart valve, the best choice is the tissue engineering heart valve(TEHV) studying.Recently, TEHV was made of acellular porcine aortic valve, and many...