The Traditional Chinese Medicine And Azone Synergy Therapy Knee Osteoarthritis Clinical And Experiment

Objective: the investigation to intend through the traditional Chinese medicine prescription—protect preparation and skin penetration enhancer—Azone synergy therapy knee osteoarthritis observe the inflammatory medium prostaglandin changes together with clinical effect standard evaluation protect knee preparation with Azone ion introduction by means of improving organize prescription and to promotion effect and drug produce provide base and pathway retrieval the reliable effect micro-ill effect convenient operation external cure method.Method: the investigation utilization vermizym joint cavity injection fabrication knee osteoarthritis animal model. According to diagnosis standard given by American rheumatism association and Kellgren with Lawrence's radiological diagnosis standard to carry out clinical case.Diagnosis selection according to knee osteoarthritis serious index (ISOA) score for pretherapy and post-therapy effect evaluation exponent and prostaglandin concentration of joint fluid for experiment animal and experiment case congenerous measure marker.Animal experiment: health 6-8 month newzerland white rabbits of 35 female and male together, mono cage grooming.