Clinical Study On The Effect Of "Jade Screen Powder And Paeonia Glycyrrhiza Uralensis Tang" To Cure Varicose Veins Of Lower Extremity

Background and destinationVaricose veins of lower extremity is because of the functional defect of the valvula of Veins of lower extremity, the defilade of the Venous blood recirculation, the sign the physical sign and complication is acutely effect the performance mood and the quality of life. According to the statistics of our country, there are about 80million to a hundred million patients, the disease incidence is ahout 9. 26%, quor it the male' morbidity rate is 11. 5%, the femail' is 6.46%. The morbidity rate in the primary disease is much higer in the industry developed country than in the developing country. Following our country entering the senescence society and the development of the industry, the morbidity rate in the primary disease will be step up further.The etiopathogenisis pertaining to Varicose veins of lower extremity, In 1916, Homans indicated that Varicose veins of lower extremity is because of the weak of the Wall of vein and the boold reflux which casued by the Valvular incompetence, or because of the deep venous thrombosis, the cavitas pelvis tumour and the encyesis ect which can induce the blood curren change lock. The contemporary consider the weak of Wall of vein and the defect of valvula venosa is a display of the sys. supporting tissue, which is relate to the genetic factor. The . formation Varicose veins of lower extremity is also tightly close to the acquired predisposition, such as Chronic cough, habitual constipation, long-term standing work ect wich can aggravate the gravitation of the extremitas inferior blood, accordingly result the Varicose veins of lower extremity. But according to the improvement of the angiography and vascular surgery. lOyears ago people gradually realized that Varicose veins of lower extremity is the syn- morbidity of the primar functional defect of the valvula of Veins of lower extremity, or the deuteropathy of deep venousthrombosis of lower limb. Scholars keep on researching the new mechanism, Qiao is studing from the apoptosis and blood vessel remodeling angle to studying varicose veins, discoved the increase of vein collagen content, the cell excess apoptosis and the cellulosity decrease could result vein blood vessel remodeling, this can relate varicose veins. However, these theory can not satisfactly explain the cause and the developmentof the varicose veins.In traditional medicine , Varicose veins of lower extremity is belong to the category of "ecthyma" and "nodular varicosity" ,. pathogenesis is "QI" , durable standing or weight loading, exertion wasting QI-blood, or collapse of middle-warmer energy, can influence region QI-blood circulation, Ql-stagnant and hemagglutinin cause it. Deficiency is the origin, stagnated blood is sign. So,it cause the desease.There are many methods in this desease therapy, such as operation, micro operation, drug treatment, sclerosing therapy and traditional Chinese medicine therapy. Now it is generally consider that Stripping of varicose veins is the gold standard to cure Varicose veins of lower extremity. But operation is only considered to use when Varicose veins of lower extremity is manifes, or the complication occur and the work is effected. Furthermore, most of the patient is willing to accept drug treatment, easily operation. This research is plan to make prospective trabant control study on the Varicose veins of lower extremity patients who are in hospital or out-patient in GuangDong province traditional Chinese medical hospital.. summarize and analyze the therapeutic effect of "Jade Screen Powder and Paeonia Glycyrrhiza uralensis tang" to cure Varicose veins of lower extremity which Professor Cai Bingqin used. MethodThe patient who are consistent with internalize standard will be random allocated two sets by 1: 1 to do expectant treatment for 1 month, by observing the objective indicatrix, study and analysis the therapeutic effect of the Chinese crude drug group (Jade Screen Powder and Paeonia Glycyrrhiza uralensis tang) and the Western medicine group Result(DThe comparison disparation of Chinese crude drug group and the Western medicine group' s total effective rate and excellence rate on curing Varicose veins of lower extremity have not the statistical significance. (P>0. 05) .(2)To deficiency of vital energy patients, the comparison disparation of Chinese crude drug group and the Western medicine group' s total effective rate and on curing Varicose veins of lower extremity have not the statistical significance. (P>0. 05) .There are significant deviation on comparing every the tris- grade therapeutic effectand between two sets (P<0. 05) .(3)There are significant deviation on the complication of Varicose veins of lower extremity Chinese crude drug group and the Western medicine group (P<0. 05) .(4)There are significant deviation on lessening the Edema of lower extremity of Varicose veins of lower extremity Chinese crude drug group and the Western medicine group (P<0. 05) . Cone I us ion"Jade Screen Powder and Paeonia Glycyrrhiza uralensis tang " complex prescription' curative effect is better on curing the deficiency of vital energy patients' Varicose veins of lower extremity than control group.