Study On The Chemical Constituents Of The Leaves Of Bramble

In rats, oral administration the extract of Bramble leaves lowed blood glucose leaves. This study was in order to investigate the constituents of the leaves. The paper were including two parts:partⅠ: This paper discovered the efficient part of leaves of Bramble is RW , the active substance is exist in W30 and efficient dosage is the 50-100mg/Kg, the whole process was monitored by bioactivity-guided.partⅡ: W30 was distilled and separated by combinative use of resin ,silica gel chromatography and the layer chromatographic method .As a result , six compounds were identified ,which included:D-Glucosyl 2α,3β,23-trihydroxy ursa-12,18-dien-28-oate; 2α,3β,19α-trihydroxy-23-methel ursa-12-en-28-O-βglucopyanosyl ; 2α,3β,19α-trihydroxy ursa-12-en-28-O-βglucopyanosyl;2α,3α,19α-trihydroxy Olean-11,13-dien-28-O-βglucopyanosyl; 2α,3β,19α-trihydroxy Olean-11,13-dien-28-O-βglucopyanosyl.At present, the compounds were found from the Bramble leaves for the first time.