| Objective: To systematically review the effectiveness of Medicated γ-IUD for contraception, and provide evidence for the decision-making in use of Medicated y-IUD.Methods: MEDLINE, EMBASE, Cochrane Library, CBMdisc, VIP, CJFD, 10 related journals and references of included studies were searched for randomized controlled trials(RCTs) and quasi- randomized controlled trials(Quasi-RCTs) on the comparison of effectiveness between Medicated γ-IUD and other IUDs. Two reviewers independently screened the studies for eligibility, evaluated the quality and extracted the data from the eligible studies, with confirmation of cross-check. Different opinions were consulted by the third party. Meta-analysis was done by Revman 4.2. Data were pooled using fixed effect model if without heterogeneity(α>0.05), otherwise , sensitivity analysis, subgroup analysis or randomized effect model was adopted.Results: Eleven original studies(1 is ongoing and included 6300 participants, and other 10 has been published included 9752 participants) met inclusion... |
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