Study On The Ultrastructure Of Craniopharyngioma And The Expression Of Caspase-3, -9 In Craniopharyngiomas

Objective: To investigate the ultrastructure of craniopharyngioma and the exprssion and significance of Caspase-3,-9 in craniopharyngiomasMethods: 1) The cell apoptosis in craniopharyngioma and normal brain tissue was inspected by mean of TUNEL technique and four cases of fresh craniopharyngioma samples was used to examine by means of electromicroscope. 2) The expression of Caspase-3, -9 were detected in 50 cases of craniopharyngiomas and 10 cases of normal brain tissues by immunohistochemical SP technique and the outcome were determined by the standard of China Pathology Magazine Editorial Committee about The Special Seminor of Nationwide Iramuohistochemistry Technique and Diagnosis Standardization instituted in 1996 and were analyzed by statistical method. Results: 1 HE observation: (1) Histological characteristics of adamantine epithelial craniopharyngiomas: the epithelial components looked like strips or nests .Basis cells looked like Column or short column and arranged in order like barriers in the circumjacent region . Squamous and star cells were located inside the nest. (2)Histological characteristics of squamous papillary craniopharyngiomas: solid parts consisted of sheet squamous...