The Influences Of Different Patterns Of Mechanical Stretches On Osteoblast Mitochondrial Membrane Potential Fluctuation

[Background & Objectives] Pathological degeneration of alveolar bone has become the major blockade that drastically limits the long-term outcomes of various prostheses. An innovative osteoblast-based biotherapy could be the only way out. Mitochondrial membrane potential is closely associated with cell function, playing significant roles in different stages of osteoblast differentiation. However, our knowledge towards the correlation between different patterns of mechanical stimuli and corresponding mitochondrial membrane potential responses are scarce. This project is designed to demonstrate the correlation between various patterns of stretches and the corresponding fluctuation of mitochondrial membrane potential and cellular proliferation index. [Materials & Methods] Human osteosarcoma originated MG63...