Prophylactic Effect Of Gabexate On Post-ERCP Pancreatitis: A Clinical Observation

Objectives: To examine the Prophylactic effect of Gabexate on post-ERCP pancreatitis, hyperamylasemia and other complications.Methods: A total of 95 patients were entered the trial and were randomly divided into three groups: groupâ… ,â…¡and placebo groups. Estimation of pancreatitis,hyperamylasemia and other complications incidence were performed in all patients.Results: Acute pancreatitis was clinically established in 7.41% in gabexate groupâ… ,3.12% in groupâ…¡and 2.78% in placebo group;55.56% of patients were complicated with hyperamylasemia in gabexate groupâ… , 43.75% in gabexate groupâ…¡and 41.67% in placebo group; The difference between three groups was not prominent; Other incidence of complications such as pancreatic pain abdominal distension,nausea,emesis,bleeding between three groups was also not prominent.Conclusions: Low dose of gabexate infused before ERCP may not effectively prevent the occurrence of hyperamylasemia,post-ERCP pancreatitis and other complications...