Background and objective: Pituitary adenoma is a tumor of the pituitary gland which contributes 5-10% of the intracranial tumors. They arise from the anterior portion of the gland and usually benign. They are most common in 3rd and 4th decade of life and affect both sexes equally. The main aim of this study is to evaluate the feasibility and therapeutic effectiveness of 3 different surgical approaches on different types of pituitary adenoma and to study the relation between 3 different approaches and types, amount of tumor resection and grading in suprasellar extension of the pituitary adenoma. We described 3 different surgical approaches (transphenoidal surgery, sub-frontal craniotomy and pterional craniotomy), presented and reviewed of 50 cases undergoing these procedures with emphasis on patient selection, surgical technique, endocrinological study, post operative complications and post operative adjunctive therapy.Method: A retrospective review was performed of patients who had undergone transphenoidal surgery (TSS), sub-frontal craniotomy and pterional craniotomy approach...
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