The Relationship Of Free Fatty Acid,Nuclear Factor Kappa-B And The Diabetic Macrovascular Complications In Type 2 Diabetes Mellitus

Background and ObjectiveDiabetes metilltus is one of the life-threatening epidemic diseases, which forms the third death rate just next to the cardiovascular diseases, cerebrovascular diseases and cancer. The high mortality and disaiblity rate is characteristics of the diabetic complication. The diabetic vascular complication is comprised of macrovascular diseases and microvascular diseases. United Kingdom Prospective Diabetes Study are the most sweeping and longest time visiting random compare test research, aimed at realizing the relation of control the plasma glucose and vascular complication in T2DM . They found that intense contract of plasma glucose could obviously reduce the microvascular complication and couldn't do the macrovascular complication, the effect was few. It can be seen that a lot of matters influenced the macrovascular diseases of T2DM.Fattiness change and the relationship of the mechanism of diabetes and It's macrovascular complication are the important medical question in domestic and international. The fat of the organism is updated incessantly. On the one hand, the outside fat enter fatty cell through the plasma by the free fatty acid (FFA), then synthesize fat to store, most of intrinsic fat are synthesized in the liver , they also through the plasma by the FFA enter into the fatty cell to store . On the other hand, the stored fat degraded perpetually. They enter each of organization with FFA form, are...