Effects Of Cochlear Blood Vessels Sympathetic Denervation On The Cochlear Blood Flow And Auditory Physiologic Function In Guinea Pigs

AIM: To investigate the detailed innervation patterns of the sympathetic nerve to the cochlear blood vessels and related neurotransmitters in the guinea pig; Also investigate the effects of superior cervical sympathectomy on cochlear blood flow and auditory physiologic function in guinea pigs.METHODS: (1) The spiral modiolar artery(SMA) in guinea pig cochlea was exposed by microsurgery, then the fluorogold(FG) or horseradish peroxidase(HRP) was given around the SMA for retrograde tracing. The bilateral superior cervical ganglia(SCG),stellate ganglia(STG) and trigeminal ganglion(TG) were observed to find out retrogradely labeled neurons. (2) The neurotransmitters of the...